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Sunday, 20 August 2017

ABSENCE OF IN VIVO MUTAGENIC POTENCY OF HEATED AND FRIED OILS IN MICE

Ayurveda is the science and know how of human living in a better way. It is perfected over thousands of years in India. This blog trying to explore all the secrets Ayurveda in a simple and palatable form and named it as "Ayurvedya". It is wish and grace of Pujya Sadguru Deva. JGD
Abstract no :  3-1...4-SV-359
Author(s) :  (Dept. of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, 570 003, India)
Address :  Narasimhamurthy, K.; Muralidhara; Raina, P. L.
Source :  Indian Journal of Experimental Biology, v. 37(1); p.50-55, 1999
Title :  ABSENCE OF IN VIVO MUTAGENIC POTENCY OF HEATED AND FRIED OILS IN MICE
Abstract :      The mutagenic potency of peanut (Archis hypogaea) (BHUCHANAKA), sesame (Sesamum indicum) (TILA) and coconut (Cocos nucifera) (NARIKELA) oils was studied employing two in vivo mammalian assays, viz., bone marrow micronucleus assay and the sperm morphology assay in albino mice. In the bone marrow micronucleus assay oral doses of fresh, heated and fried oils (7.5 ml and 30.0 ml/kg body weight) did not induce any increase in the incidence of micro-nucleated polychromatic erythrocytes. Intra-gastric administration of oils at the highest dose (30.0 ml/kg body weight/day) for 5 consecutive days in male mice did not produce any morphological effect either on the testicular or epididymal weights and histology. No significant alterations were observed in the caudal sperm counts any of the sampling intervals and also there was no treatment related increase in the incidence of sperm head abnormalities.

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